Invest in ME Research is an independent UK charity finding, facilitating and funding a strategy of biomedical research into Myalgic Encephalomyelitis (ME or ME/CFS), and promoting better education about ME. The charity is run by volunteers with no paid staff. Invest in ME Research is a founder member of the European ME Alliance (EMEA), a collaboration of European national charities and organisations. The charity was responsible for initiating the European ME Research Group (EMERG), a collaboration of European researchers from major institutes, and also the European ME Clinicians Council (EMECC), a network of European clinicians working together and sharing experiences of treating ME in order to establish better standards for patient care. The charity organises an annual international research Colloquium and public conference regularly attracting delegates from 20 countries. These events provide a platform for research and a means of facilitating education about ME. The charity funds biomedical research in support of our proposal for a UK/European Centre of Excellence for ME and has recently funded a major clinical trial for ME. We also facilitate and fund research that influences collaboration within Europe. In order to make rapid progress in treating ME and to find and facilitate the best strategy of research into this disease the charity welcomes support for our work.